Adenoviral Custom Services

Welgen offers an improved technology to simplify and accelerate the construction of adenoviral vectors, which offer many advantages to investigators who study gene expression or gene silencing in mammalian systems. Adenoviruses have a strong safety record and recombinant adenoviral vectors have been useful tools for gene function studies as well as for human gene therapy. Recombinant adenoviruses that cannot replicate are attractive vectors for gene delivery for several reasons:

  • they infect many types of mammalian cells with high efficiency
  • they do not disrupt the genome of the host cell but remain in the nucleus as episomal DNA
  • they provide transient, high level gene expression
  • they are suitable for both in vitro and in vivo applications

Welgen provides a complete line of adenoviral services:

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Service IDServiceEstimated Price*
S1100Construct an Adenovirus Vector to Express a Gene (target cDNA provided by customer)
S1200Construct an Adenovirus Vector to Express a Gene (target cDNA not provided by customer)
S1300Generation of Adenovirus (adenoviral construct provided by customer)
S2100Construct a pQuiet Vector to Silence Gene Expression
S2200Construct an Adenovirus to Silence Gene Expression
S2300RNAi Selection and Validation Service
S3000Amplification and Purification of Adenovirus (3 ml)
S3010Amplification and Purification of Adenovirus (1 ml)
S3110Plaque Purification
S3120Plaque Assay to Titer Adenovirus
S3130PCR Assay for RCA
S3140RCA Assay in A549 Cells
S3160Isolate Adenoviral DNA Sample
S3170MOI Assay